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Germ cell transplants produce functional gametes

Monday, 01 October 2007 22:57 UTC

Primordial germ cells (PGC) were transplanted across species, even across genera, into zebrafish with host PGC inactivated by Dead End Morpholinos (and offspring were produced from daughter cells of the transplanted PGC after natural spawning):
Saito T, Goto-Kazeto R, Arai K, Yamaha E.
Xenogenesis in Teleost Fish Through Generation of Germ-Line Chimeras by Single Primordial Germ Cell Transplantation.
Biol Reprod. 2007 Sep 26; [Epub ahead of print]

Updated 02 October 2007 00:01 UTC