Recent replies to "Q: Glycomics by MS at high throughput - a reality ?" http://network.nature.com/forums/http-network-nature-comgroupsglycobiology/1518 en-us 40 <p>The readers of this thread could find interesting to know that version 1.0 of GlycoWorkbench has just been released.</p> <p>GlycoWorkbench is a free tool for semi-automatic interpretation of MS data of glycans. GlycoWorkbench is not totally automated but also it is not restricted to mammalian n-glycans.</p> With GlycoWorkbench the user can: draw glycan structures in <span class="caps">CFG</span> notation and export them in several standard formats <ul> <li>compute glycan masses for different type of markers and derivatization</li> <li>find glycan compositions matching the desired mass values</li> <li>find glycan structures in open access databases (CFG, CarbBank, GlycoSciences)</li> <li>find the fragments of the drawn structures matching the mass values</li> <li>annotate a peak list with both intact structures, compositions and fragments<br />* load, explore and annotate raw mass spectra from several formats (mzXML, <span class="caps">ABI</span>, Bruker, Thermo, Waters)</li> <li>create graphical reports of the annotated spectra similar to those found in the Functional Glycomics pages</li> </ul> <p>The basic features of the tool are described in a recent publication on the Journal of Proteome Research (<a href="http://pubs.acs.org/cgi-bin/abstract.cgi/jprobs/2008/7/i04/abs/pr7008252.html">link</a>).</p> <p>The tool can be freely downloaded from <a href="http://www.eurocarbdb.org/applications/ms-tools">link</a></p> Thu, 15 May 2008 10:24:12 -0000 http://network.nature.com/forums/http-network-nature-comgroupsglycobiology/1518?page=1#reply-4145 Alessio Ceroni http://network.nature.com/forums/http-network-nature-comgroupsglycobiology/1518?page=1#reply-4145