JOURNAL CLUB: The cellular and molecular origins of beak morphology
Heather Etchevers
Wednesday, 19 March 2008 10:14 UTC
I like this paper because it ties in molecular biology, classical embryology and evolution. I find the writing clear and use it as an example of the cross-disciplinary nature of developmental biology in my courses.
Here is the link; if you are subscribed to Science, you’ll be okay. If not, is it legal to propose that I can forward a PDF to readers?
http://www.sciencemag.org/cgi/content/full/299/5606/565
The Cellular and Molecular Origins of Beak Morphology
R. A. Schneider, J. A. Helms
Cellular and molecular mechanisms underlying differences in beak morphology likely involve interactions among multiple embryonic populations. We exchanged neural crest cells destined to participate in beak morphogenesis between two anatomically distinct species. Quail neural crest cells produced quail beaks in duck hosts and duck neural crest produced duck bills in quail hosts. These transformations involved morphological changes to non-neural crest host beak tissues. To achieve these changes, donor neural crest cells executed autonomous molecular programs and regulated gene expression in adjacent host tissues. Thus, neural crest cells are a source of molecular information that generates interspecific variation in beak morphology.
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Replies
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What I like about the paper:
- The title and abstract are very clear
- The authors find the space to put their work into a broader historical perspective by starting with Charles Darwin and On the Origin of Species and ending with Hans Spemann and the organizer effect.
- They invent the words quck and duail for their duck-quail chimeras. The authors probably didn’t know that quck can also have a different meaning.
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I’ve added the paper to the “Connotea good journal club”: http://www.connotea.org/tag/good%20paper%20journal%20club
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Sorry, forgot to check preview. Here is the Connotea link again
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