Modification of screen-printed carbon electrodes (SPCE)
Nikolay Pchelintsev
Tuesday, 04 December 2007 10:03 UTC
Dear all,
How do you think is it worth to develop complicated techniques for the surface modification of SPCE or not?
SPCE as electrochemical transducers are meant to be used in disposable biosensors. Hence both production of SPCE and the following biomaterial immobilization should be as cheap as possible and fairly quick. The latter requirement is important for the mass-production of these devices.
From this point of view electrochemical derivatisation of carbon surface (e.g. diazonium reduction) is not appropriate. On the other hand, using electrochemical methods it is possible to create highly specific affinity sites (biotin, Ni-NTA) on the electrode’s surface that hardly can be obtained in any other way.
So, what do you think about this?
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Replies
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It’s a difficult question. I think there are two way – to show principal possibility (fundamental research) or to direct your sensor toward business offer for real application. But the latter it is not possible without first. So somebody may offer principle and publish articles, somebody now how it principal use for design mass production. For example I can modify SPE with electroactive polymer by electropolymerization. Sure it is not good for commercial use but with electrochemistry I control very well this step (amount, structure, adhesion to surface) and on the other hand there are chemically synthesized electroactive polymers which may be use in future.
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