Those of you who have worked with molecular interaction databases (specially the protein-protein interaction data) know very well that heterogeneity and ambiguity of interaction data in majority of databases are two big hurdles to researchers. In order to overcome this problem, several efforts have been made including that of Oliva et al. who introduced PIANA approach for protein interactions and network analysis. Such approaches use a different parser for each database in order to transform the data into a common format.
In a paper published in Nature Biotechnology on 8 August 2007, Sandra Orchard et al. have reported a new standard namely “the minimum information for reporting a molecular interaction experiment” which proposes a guideline for bench scientists to avoid inconsistencies and missing information in their published papers. The aim of MIMIx is to follow the PSI-MI standards and to support the systematic capture of molecular interaction data in public databases.